吲哚环衍生物在直链淀粉柱上的拆分

Separation of Indole Ring Enantiomers on Amylase-tris (3, 5-dimethylphenylcarbamate) Chiral Stationary Phase

中文关键词:  手性拆分,直链淀粉-三（3,5-二甲基苯基氨基甲酸酯),吲哚环衍生物

英文关键词:chiral sepatation,ADMPC,enatiomers of indole ring derivatives

中文摘要:

      选用不同的醇改性剂，在自制的直链淀粉-三（3,5-二甲基苯基氨基甲酸酯）（ADMPC）手性固定相上，对2种吲哚环衍生物对映体进行了手性拆分研究，并考察了样品的保留时间和立体选择性.

英文摘要:

      Two enatiomers of indole ring derivatives have been chiral separated on amylase-tris (3,5-dimethylphenylcarbamate) chiral stationary phase (CSP), using hexane as the mobile phase with various alcohols as modifiers. The influence of the mobile phase composition on the enantioselectivity was discussed. By comparing the results from amylase-tris (3,5-dimethylphenylcarbamate) chiral stationary phase and cellulose tris (3, 5-dimethylphenylcarbamate) chiral stationary phase, the separation abilities are different on the two stationaries.