氨基酚异构体的离子对反相液相色谱分析的研究

Analysis of Aminophenol Isomers by Ion-Pair RP-HPLC

中文关键词:  离子对色谱  反相液相色谱  氨基酚  异构体

英文关键词:Ion-pair chromatography  RP-HPLC  aminophenol  isomer

中文摘要:

      本文研究了离子对反相液相色谱分析氨基酚异构体的可能性、影响因素和色谱条件,发现以含4×10^-8mol/L四丁基碘化铵、0.184mol/L醋酸钠的甲醇水溶液(23:77)作为流动相,ODS为固定相时可以实现氨基酚异构体的良好分离.

英文摘要:

      By comparing the analytical methods the possibility,influencing factors and ion-pairRP-HPLC conditions in analysis of aminophenol isomers have been studied.The optimumseparating conditions are as follows:the mobile phase is 4×10^-3mol·L^-1 tetrabutylammonium iodide, 0.184mol·L^-1 NaAc,23:77 methanol-water and 0.8 g·L^-1 NaHSO₃.The stationary phase is ODS.The method can be used in analysis of aminophenol isomerseffectively and fastly.