HPLC-ELSD测定茜芷胶囊中三七皂苷R1、人参皂苷Rg1及Rb1的含量

Determination of Ginsenoside Rg1, Rb1 and Notoginsenoside R1 in Qianzhi Capsules by HPLC-ELSD

中文关键词:  茜芷胶囊  三七皂苷R₁  人参皂苷Rg₁  人参皂苷Rb₁  HPLC-ELSD

英文关键词:Qianzhi Capsule  notoginsenoside R₁  ginsenoside Rg₁  ginsenoside Rb₁  HPLC-ELSD

中文摘要:

      利用HPLC-ELSD对茜芷胶囊中的活性成分三七皂苷R₁、人参皂苷Rg₁和Rb₁的含量进行测定.三七皂苷R₁、人参皂苷Rg₁及Rb₁分别在0.13~2.60、0.30~6.00、0.38~7.60μg范围内呈现良好的线性关系,平均回收率分别为98.0%(RSD1.7%),97.1%(RSD1.8%),97.0%(RSD1.5%).该方法简便、准确、重现性好,可用于茜芷胶囊的质量控制.

英文摘要:

      The content of ginsenoside Rg₁,Rb₁ and Notoginsenoside R₁ were dertermined by HPLC-ELSD.Ginsenoside Rg₁,Rb₁ and Notoginsenoside R₁ showed a good linear relationship at the range of 0.13~2.60,0.30~6.00,0.38~7.60 μg,respectivly.The average recovery was 98.0%(RSD1.7%),97.1%(RSD1.8%),97.0%(RSD1.5%),respectivly.The proposed method is simple,efficient and accurate with a good repeatability and can be used for the quality control of Qianzhi Capsules.